A Novel High-Throughput Screen Reveals Yeast Genes That Increase Secretion of Heterologous Proteins
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چکیده
منابع مشابه
A novel high-throughput screen reveals yeast genes that increase secretion of heterologous proteins.
The yeast Saccharomyces cerevisiae is an attractive host for the production of heterologous proteins. However, low-yield production of many proteins (from micrograms to milligrams/liter) leaves considerable room for optimization. By engineering the yeast cell via traceable genome-wide libraries, genes that can enhance protein expression level because of their roles in protein transcription, tra...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2007
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.02427-06